Development of spiral square coils for magnetic labelling detection in microfluidic systems

Due to the development of microfluidic systems biomedical microelectromechanical systems (BioMEMS) for magnetic labelling detection by magnetic microbeads circling in microfluidic channels, we used the magnetic field created by microcoils. The magnetic field associated with the electric current, but with negatively affects if its value increases too much. Handling bio-species in the microfluidic chip requires that the temperature maintained to keep the cells to prevent their destruction. In this paper we have described the spiral square coil design of different structures to produce an effective magnetic flux density. The simulation of the magnetic flux density is carried out with the help of the COMSOL software. We have presented an optimization of the geometric parameters of the microcoil for a better performance and a miniaturization of the structure with copper wire section S=25 µm2 and inter-wire space a=5 µm. We have also developed this microcoil by adding a ferromagnetic core to the inner center, the results obtained in this work shown that the magnetic flux density increases around 1.07 times in Bx and 1.45 times in Bz. This new approach in designing a microcoil allows to obtaining a fast trapping of the microbeads and a highly sensitive biological element detection and avoiding increase heat ratio in microfluidic systems

Design and Optimization of Inductively Coupled Spiral Square Coils for Bio-Implantable Micro-System Device

Due to the development of biomedical microsystems technologies, the use of wireless power transfer systems in biomedical application has become very largely used for powering the implanted devices. The wireless power transfer by inductive resonance coupling link, is a technic for powering implantable medical devices (IMDs) between the external and implanted circuits. In this paper we describe the design of an inductive resonance coupling link using for powering small bio-implanted devices such as implantable bio-microsystem, peacemaker and cochlear implants. We present the reduced design and an optimization of small size obtained spiral coils of a 9.5 mm2 implantable device with an operating frequency of 13.56 MHz according to the industrial scientific-medical (ISM). The model of the inductive coupling link based on spiral square coils design is developed using the theoretical analysis and optimization geometry of an inductive link. For a mutual distance between the two coils at 10mm, the power transfer efficiency is about 79% with , coupling coefficient of 0.075 and a mutual inductance value of 2µH. In comparison with previous works, the results obtained in this work showed better performance such as the weak inter coils distance, the hight efficiency power transfer and geometry

Noninvasive blood glucose monitoring system based on near-infrared method

Diabetes is considered one of the life-threatening diseases in the world which need continuous monitoring to avoid the complication of diabetes. There is a need to develop a non-invasive monitoring system that avoids the risk of infection problems and pain caused by invasive monitoring techniques. This paper presents a method for developing a noninvasive technique to predict the blood glucose concentration (BCG) based on the Near-infrared (NIR) light sensor. A prototype is developed using a finger sensor based on LED of 940 nm wavelength to collect photoplethysmography (PPG) signal which is variable depending on the glucose concentration variance, a module circuit to preprocess PPG signals is realized, which includes an amplifier and analog filter circuits, an Arduino UNO is used to analog-to-digital conversion. A digital Butterworth filterer is used to remove PPG signal trends, then detect the PPG data peaks to determine the relationship between the PPG signal and (BCG) and use it as input parameters to build the calibration model based on linear regression. Experiments show that the Root Mean Squares Error (RMSE) of the prediction is between 8.264mg/dL and 13.166 mg/dL, the average of RMSE is about 10.44mg/dL with a correlation coefficient (R^2) of 0.839, it is observed that the prediction of glucose concentration is in the clinically acceptable region of the standard Clark Error Grid (CEG)

On fractional biparameterized Newton-type inequalities

Abstract In this work, we present a novel biparameterized identity that yields a family of one-, two-, three-, and four-point Newton-type formulas. Subsequently, we establish some new Newton-type inequalities for functions whose first derivatives are α-convex. The investigation is concluded with numerical examples accompanied by graphical representations to substantiate the accuracy of the obtained results

Corrected Dual-Simpson-Type Inequalities for Differentiable Generalized Convex Functions on Fractal Set

The present paper provides several corrected dual-Simpson-type inequalities for functions whose local fractional derivatives are generalized convex. To that end, we derive a new local fractional integral identity as an auxiliary result. Using this new identity along with generalized Hölder’s inequality and generalized power mean inequality, we establish some new variants of fractal corrected dual-Simpson-type integral inequalities. Furthermore, some applications for error estimates of quadrature formulas as well as some special means involving arithmetic and p-logarithmic mean are offered to demonstrate the efficacy of our findings

Corrected Dual-Simpson-Type Inequalities for Differentiable Generalized Convex Functions on Fractal Set

The present paper provides several corrected dual-Simpson-type inequalities for functions whose local fractional derivatives are generalized convex. To that end, we derive a new local fractional integral identity as an auxiliary result. Using this new identity along with generalized Hölder’s inequality and generalized power mean inequality, we establish some new variants of fractal corrected dual-Simpson-type integral inequalities. Furthermore, some applications for error estimates of quadrature formulas as well as some special means involving arithmetic and p-logarithmic mean are offered to demonstrate the efficacy of our findings

Some new fractional Hermite-Hadamard type inequalities for functions with co-ordinated extended s,m-prequasiinvex mixed partial derivatives

This article introduces extended (s,m)-prequasiinvex functions on coordinates, a new form of generalized convex function. Using a previously established identity, we derive new fractional Hermite-Hadamard type integral inequalities for functions whose mixed partial derivatives belong to this new class of functions. The obtained results generalize existing Hermite-Hadamard type inequalities and have numerous applications in mathematics and physics. To demonstrate the utility of our findings, we provide examples of applications to special means, such as arithmetic, harmonic and p-logarithmic means